The HEAT Trial NEJM 2015

NEJM HEAT HEAT logo HEAT graph

The SPLIT Trial JAMA 2015

Original Wellington Research

Saline vs Plasma-Lyte 148
JAMA SPLIT SPLIT logo SPLIT graph

Original Medical & Nursing Research from Wellington ICU

Resuscitation Psirides Chimpanzee Psirides HOTorNOT

The ANZICS CTG World-leading Australasian Research

Clinical Trials Group collaboration

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Wellington Investigator Led Multicentre Randomised Controlled Trials

HOTorNOT ICU-ROX PEPTIC

Publications From Wellington ICU

Authors working in Wellington ICU at the time of publication are listed in bold.
Most recent publications are listed first and are grouped by publication date.
Wellington ICU has also participated in many ANZICS CTG trials, with our medical specialists acting as co-investigators. These are also listed below.

Please select the relevant year to expand. Number of publications in parentheses.

2017 (9)
  • Deane AM, Hodgson CL, Young P, Little L, Singh V, Poole A, Young M, Mackle D, Lange K, Williams P, Peake SL, Chapman MJ, Iwashyna TJ. The rapid and accurate categorisation of critically ill patients (RACE) to identify outcomes of interest for longitudinal studies: a feasibility study. Anaesth Intensive Care 2017 Jul;45(4):476-484
  • Smith G, Prytherch D, Psirides AJ. Chapter 15: An Overview of the Afferent Limb. Textbook of Rapid Response Systems: concept & implementation 2nd ed. Springer 2017 Jul
  • Jones D, Holmes J, Currey J, Fugaccia E, Psirides AJ, Singh MY, Fennessy GJ, Hillman K, Pilcher DV, Bellomo R, DeVita M. Proceedings of the 12th International Conference on Rapid Response Systems and Medical Emergency Teams. Anaesth Intensive Care 2017 Jul;45(4):511-517
  • Ridgeon E, Bellomo R, Aberegg S, Mac Sweeney R, Varughese R, Landoni G, Young P. Effect sizes in ongoing randomised controlled critical care trials. Critical Care 2017 June; 21:32
  • Khanna A, English S, Wang X, Ham K, Tumlin J, Szerlip H, Busse :, Altaweel L, Albertson T, Mackey C, McCurdy M, Boldt D, Chock S, Young P, Krell K, Wunderink R, Ostermann M, Murugan R, Gong M, Panwar R, Hastabacka J, Favory R, Venkatesh B, Thompson T, Bellomo R, Jensen J, Kroll S, Chawla L, Tidmarsh G, Deane A. Angiotensin II for the Treatment of Vasodilatory Shock. New England Journal of Medicine. 2017 May
  • Perner A, Browne J, Joannidis M, Young P, Hjortup P, Pettilä V. Fluid management in acute kidney injury. Intensive Care Medicine. 2017 May
  • Reddy S, Bailey M, Beasley R, Bellomo R, Mackle D, Psirides A, Young P. Effect of 0.9% Saline or Plasma-Lyte 148 as Crystalloid Fluid Therapy in the Intensive Care Unit on Blood Product Use and Postoperative Bleeding after Cardiac Surgery. Journal of Cardiothoracic and Vascular Anesthesia. 2017 Apr
  • Ritzema J, Young P. Editorial - Admitting elderly patients to ICU, Is it just about survival. New Zealand Medical Journal. 2017 Apr;130(1453):8-10
  • Young P, Bailey M, Beasley R, Beasley RW, Freebairn RC, Hammond NE, Haren FM, Harward ML, Henderson SJ, Mackle DM, McArthur CJ, McGuinness SP, Myburgh JA, Saxena MK, Turner A, Webb SA, Bellomo R. Protocol and statistical analysis plan for the Randomised Evaluation of Active Control of Temperature versus Ordinary Temperature Management (REACTOR) trial. Crit Care Resusc. 2017 Mar;19(1):81-87
REACTOR study
2016 (29)
  • Sutton L, Jarden R. Improving the quality of nurse-influenced patient care in the intensive care unit. Nursing in Critical Care 2016 Dec
  • Joint College of Intensive Care Medicine and Australian and New Zealand Intensive Care Society Special Interest Group on Rapid Response Systems. Resource use, governance and case load of rapid response teams in Australia and New Zealand in 2014. Crit Care Resusc 2016 Dec;18(4):275-282
  • Chalwin R, Radford S, Psirides A, Laver R, Bierer P, Rai S, Knott C, Dyett J, Jones D. Participant perceptions of a rapid response team training course. Crit Care Resusc 2016 Dec;18(4):283-288
  • Coombs M, Mitchell M, James S, Wetzig K. Intensive care bereavement practices across New Zealand and Australian intensive care units: a qualitative content analysis. Journal of Clinical Nursing 2016 Nov.
  • Young P, Bellomo R, Landoni G. Letter: timing of initiation of renal replacement therapy in critically ill patients with acute kidney injury. JAMA 2016;316(11):1213-1214
  • Bellomo R, Landoni G, Young P. Improved survival in critically ill patients: are large RCTs more useful than personalised medicine? Yes. Intensive Care Med 2016 Sep
  • Reddy S, Bailey M, Beasley R, Bellomo R, Mackle D, Psirides A, Young P. Effect of saline 0.9% or Plasma-Lyte 148 therapy on feeding intolerance in patients receiving nasogastric enteral nutrition. Crit Care Resusc 2016 Sep;18(3):198-204
  • Young P, Machado F, Finfer S. What's new on balanced crystalloid solutions? Intensive Care Med 2016 August
  • Casemento A, Bellomo R, Young P. Reply to Letter: Could one degree in temperature change the world? Maybe for targeted temperature management! Resuscitation 2016 August
  • Casemento A, Minson A, Radford S, Martensson J, Ridgeon E, Young P, Bellomo R. A comparison of therapeutic hypothermia and strict therapeutic normothermia after cardiac arrest. Resuscitation 2016 June;106:83-88
  • Young P. Acetaminophen to treat fever in intensive care unit patients with likely infections: a response from the author of the HEAT trial. Journal Thoracic Diseases 2016
  • Psirides A, Hill J, Jones D. Rapid Response Team activation in New Zealand hospitals - a multicentre prospective observational study. Anaesth Intensive Care 2016;44(3):391-397
  • Young P. Saline Is the Solution for Crystalloid Resuscitation. Crit Care Med 2016 May
  • Young P, Bailey M, Bellomo R. Aute Kidney Injury with Buffered Crystalloid vs Saline Among ICU Patients - Reply. JAMA 2016;315(14):1521
  • Hales C, de Vries, K, Coombs M. Managing social awkwardness when caring for morbidly obese patients in intensive care: a focused ethnography. Int Journ Nursing Studies. 2016 June; 58:82-89
  • Young P, Saxena M, Beasley R. Correspondence: Acetaminophen for Fever in Critically Ill Patients with Suspected Infection. NEJM 2016 March 31;374:1291-1293
  • Tipping C, Bailey M, Bellomo R, Berney S, Buhr H, Denehy L, Harold M, Holland A, Higgins A, Iwashyna T, Needham D, Presneill J, Saxena M, Skinner E, Webb S, Young P, Zanni J, Hodgson C. The ICU mobility scale has construct and predictive validity and is responsive - a multicenter observational study. Annals of the American Thoracic Society. 2016 Mar
  • Coombs M, Nelson K, Psirides A, Suter N, Pedersen A. Characteristics and dying trajectories of adult hospital patients from acute care wards who die following review by the rapid response team. Anaesth Intensive Care. April 2016. 44(2):262-269
  • Coombs M, Tang J, Long-Sutehall T. Vigilant attentiveness in families observing deterioration in the dying intensive care patient: a secondary analysis study. Intensive and Critical Care Nursing. April 2016.33:65-71
  • Reddy S, McGuinness S, Parke R, Young P. Choice of fluid therapy and bleeding risk after cardiac surgery. Journal of Cardiothoracic and Vascular Anesthesia.
  • Reddy S, Weinberg L, Young P. Review: Crystalloid fluid therapy. Critical Care 2016. 20:59
  • Hodgson C, Bailey M, Bellomo R, Berney S, Buhr H, Denehy L, Gabbe B, Harold M, Higgins A, Iwashyna T, Papworth R, Parke R, Batman S, Presneill J, Saxena M, Skinner E, Tipping C, Young P, Webb S. Trial of Early Activity and Mobilisation Study Investigators. Crit Care Med. 2016 Mar 10
  • Reade M, Eastwood G, Bellomo R, Bailey M, Bersten A, Cheung B, Davies A, Delaney A, Ghosh A, van Haren F, Harley N, Knight D, McGuiness S, Mulder J, O’Donoghue S, Simpson N, Young P. Effect of Dexmedetomidine Added to Standard Care on Ventilator-Free Time in Patients With Agitated Delirium. JAMA. 2016 Mar 15
  • Ridgeon E, Young P, Bellomo R, Mucchetti M, Limbo R, Landoni G. The Fragility Index in Multicenter Randomized Controlled Critical Care Trials. Crit Care Med. July 2016;44(7):1278-1284
  • Ridgeon E, Bellomo R, Myburgh J, Saxena M, Weatherill M, Jahan R, Arawwawala D, Bell S, Butt W, Camsookai J, Carle C, Cheng A, Cirstea E, Cohen J, Crenshaw J, Delaney A, Eastwood G, Eliott S, Franke U, Gartner D, Green C, Howard-Griffin R, Inskip D, Litton E, MacIsaac C, McCairna A, Mahambrey T, Moondi P, Newby L, O’Connor S, Pegg C, Pope A, Reschreieter H, Richards B, Robertson M, Rodgers H, Shehabi Y, Smith I, Smith J, Smith N, Tilsley A, Whitehead C, Willett E, Wong K, Woodford C, Wright S, Young P. Validation of a classification system for causes of death in critical care: an assessment of inter-rater reliability. Crit Care Resusc. Mar 2016;18(1):50-54
  • Myers J, Powell D, Psirides A, Hathaway K, Aldington S, Haney M. Non-technical skills in the critical care air ambulance environment: introduction of an adapted rating instrument - an observational study. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. Mar 2016;24(24)
  • Kallesen M, Psirides A, Huckabee M-L. Comparison of Cough Reflex Testing with Videoendoscopy in Recently Extubated ICU Patients. Journal Crit Care. Feb 2016.
  • Sutton L, Jutel A. Alcohol withdrawal syndrome in critically ill patients: identification, assessment and management. Crit Care Nurse. Feb 2016;36(1):28-38
  • Rosemergy I, Psirides A, Adler J. Cannabidiol oil in the treatment of super refractory status epilepticus. A case report. Seizure 35 (2016) 56-58
2015 (19)
  • Mullins C, Psirides A. Activities of a Medical Emergency Team - a prospective observational study of 795 calls. Anaesthesia and Intensive Care 2016;44(1):34-43
  • Kumar A, Psirides A, Maheshwari N, Chawla V, Mandal A. Framework for decision-making and management of end-of-life decisions in Intensive Care Units: A modified protocol. Indian Journal of Critical Care Medicine 2015 Nov. 19(11):655-660
  • Young P, Bailey M, Beasley R, Henderson S, Mackle D, McArthur C, McGuinness S, Mehrtens J, Myburgh J, Psirides A, Reddy S, Bellow R. Effect of a Buffered Crystalloid Solution vs Saline on Acute Kidney Injury Among Patients in the Intensive Care Unit. The SPLIT Randomised Clinical Trial. JAMA. 2015;314(16):1701-1710
SPLIT trial
  • Young P, Saxena M, Bellomo R, Freebairn R, Hammond N, van Haren F, Holliday M, Henderson S, Mackle D, McArthur C, McGuinness S, Myburgh J, Weatherill M, Webb S, Beasley R. Acetaminophen for Fever in Critically Ill Patients with Suspected Infection. The HEAT Trial. NEJM. 2015; 373:2215-2224
Stacks Image 91466
  • Peake S, Young P, Chapman M. Correspondence: ‘Permissive Underfeeding or Standard Enteral Feeding in Critical Illness’. NEJM. 2015 Sep; 373:1173-1176
  • Panwar R, Hardie M, Bellomo R, Barrot L, Eastwood GM,6, Young PJ, Capellier G, Harrigan PW, Bailey M. Conservative Versus Liberal Oxygenation Targets for Mechanically Ventilated Patients - a Pilot Multicenter Randomized Controlled Trial. Am J Respir Crit Care Med 2015 Sep 3
  • Young PJ, Beasley RW, Capellier G, Eastwood GM, Webb SA. Oxygenation targets, monitoring in the critically ill: a point prevalence study of clinical practice in Australia and New Zealand. Crit Care Resusc. 2015 Sep; 17(3):202-7
  • Walker LJC, Young P. Fluid administration, vasopressor use and patient outcomes in a group of high-risk cardiac surgical patients receiving postoperative goal-directed haemodynamic therapy: a pilot study. Anaesthesia and Intensive Care. 2015 Sep; 43 (5)
  • Saxena M, Taylor C, Hammond N, Young P, Mysore J, Bilot L, Myburgh A, Myburgh J. A multi centre audit of temperature patterns after traumatic brain injury. Crit Care Resusc. 2015 Jun; 17(2):129-34
  • Young P. The illusion of physiological gain and rise of ‘less is more’. Editorial, Intensive Care Monitor. 2015 May/June, Vol.22, Issue 3.
  • Jones D, Hicks P, Currey J, Holmes J, Fennessy GJ, Hillman K, Psirides A, Rai S, Singh MY, Pilcher DV, Bhonagiri D, Hart GK, Fugaccia E. Findings of the first ANZICS conference on the role of intensive care in Rapid Response Teams. Anaesthesia and Intensive Care. 2015 May. 43(3):369-379
  • The SUP-ICU co-authors. Stress ulcer prophylaxis in the intensive care unit: an international survey of 97 units in 11 countries. Acta Anaesthesiologica Scandinavica. 2015 May. 59(5):576-585
  • The SUP-ICU co-authors. Prevalence and outcome of gastrointestinal bleeding and use of acid suppressants in acutely ill adult intensive care patients. Intensive Care Med. 2015 April: doi:10.1007/s00134-015-3725-1
  • Kallesen M, Psirides A, Huckabee M. Recovery of Cough Following Extubation after Coronary Artery Bypass Grafting: A Prospective Study. Journal of Critical Care. 2015 Mar: doi:10.1016/j.jcrc.2015.03.013
  • Donnelly S, Psirides A. Relatives’ and staff’s experience of patients dying in ICU. Quarterly Journal of Medicine. 2015 Mar: doi:10.1093/qjmed/hcv059
  • Reddy SK, Young PJ, Beasley RW, Mackle DM, cGuinness SP, McArthur CJ, Henderson SJ, Weinberg L, French CJ, Orford NR, Bailey MJ, Bellomo R. Overview of the study protocols and statistical analysis plan for the Saline versus Plasma-Lyte 148 for Intravenous Fluid Therapy (SPLIT) research program. Crit Care Resusc. 2015 Mar;17(1):29-36
SPLIT trial
  • The TEAM Study Investigators. Early mobilization and recovery in mechanically ventilated patients in the ICU: a bi-national, multi-centre, prospective cohort study. Critical Care. 2015 Feb: doi:10.1186/s13054-015-0765-4
  • Saxena M, Young P, Pilcher D, Bailey M, Harrison D, Bellomo R, Finfer S, Beasley R, Hyam J, Menon D, Rowan K, Myburgh J. Early temperature and mortality in critically ill patients with acute neurological diseases: trauma and stroke differ from infection. Intensive Care Medicine. 2015 Feb.
  • Tripp DG, Purdie G, Hicks P. Trends in the incidence of intensive care unit invasive mechanical ventilation and subsequent 2-year survival in very elderly New Zealanders. Intern Med J. 2015 Jan;45(1):80-5
2014 (17)
  • Weinkove R, Bailey M, Bellomo R, Saxena M, Tam C, Pilcher D, Beasley R, Young P. Association between early peak temperature and mortality in neutropenic sepsis. Annals of Haematology. Dec 2014: doi 10.1007/s00277-014-2273-z
  • Hodgson C, Stiller K, Needham D, Tipping C, Harold M, Baldwin C, Bradley S, Berney S, Caruana L, Elliott D, Green M, Haines K, Higgins A, Kaukonen K, Leditschke I, Nickels M, Paratz J, Patman S, Skinner E, Young P, Zanni J, Denehy L, Webb S. Expert consensus and recommendations on safety criteria for active mobilisation of mechanically ventilated critically ill adults. Critical Care 2014, 18:658
  • Reddy S, Bailey M, Beasley R, Bellomo R, Henderson S, Mackle D, McArthur C, Mehrtens J, Myburgh J, McGuinness S, Psirides A, Young P. The SPLIT study: a protocol for a multicentre cluster-randomised double crossover study of 0.9% saline vs. Plasma-Lyte 148 for intensive care fluid therapy. Crit Care Resusc 16(4):274-279
  • Young P, Joannidis M. Crystalloid fluid therapy: is the balance tipping towards balanced solutions? Intensive Care Medicine. Nov 2014. doi:10.1007/s00134-014-3531-1
  • Young P, Bailey M, Bellomo R, Bernard S, Dicker B, Freebairn R, Henderson S, Mackle D, McArthur C, McGuinness S, Smith T, Swain A, Weatherall M, Beasley R. Hyperoxic therapy or normoxic therapy after out-of-hospital cardiac arrest (HOT OR NOT): a randomised controlled feasibility trial. Resuscitation. 2014. doi:10.1016/j.resuscitation.2014.09.011
HOTorNOT
  • Eastwood GM, Litton E, Bellomo R, Bailey MJ, Festa M, Beasley RW, Young PJ. Opinions and practice of stress ulcer prophylaxis in Australian and New Zealand intensive care units. Crit Care Resusc. 2014 Sep;16(3):170-4
  • Litton E, Eastwood GM, Bellomo R, Beasley R, Bailey MJ, Forbes AB, Gattas DJ, Pilcher DV, Webb SA, McGuinness SP, Saxena MK, McArthur CJ, Young P. A multicentre feasibility study evaluating stress ulcer prophylaxis using hospital-based registry data. Crit Care Resusc. 2014 Sep;16(3):158-63
  • Panwar R, Young P, Capellier G. Conservative oxygen therapy in mechanically ventilated patients. Crit Care Med. 2014 Sep;42(9):e630-1
  • Gantner D, Farley K, Bailey M, Huckson S, Hicks P, Pilcher D. Mortality related to after-hours discharge from intensive care in Australia and New Zealand, 2005-12. Intensive Care Medicine. doi: 10.1007/s00134-014-3438-x
  • Pilcher D, Hicks P, Huckson S. Intensive Care registries in Australia and New Zealand. ICU Management 2014 13(4):44-47
  • Jarden R, Sutton L. A practice change initiative to improve the provision of enteral nutrition to intensive care patients. Nursing in Critical Care. doi: 10.1111/nicc.12107
  • Eastwood GM, Young PJ, Bellomo R. The impact of oxygen and carbon dioxide management on outcome after cardiac arrest. Curr Opin Crit Care. 2014 Apr 8.
  • Young PJ, Delaney AP, Dulhunty JM, Venkatesh B. Critical care statistical analysis plans. In reply. Crit Care Resus. 2014 Mar; 16(1) 76-7
  • Hodgson C, Berney S, Haines K, Harrold M, Young P, Buhr H, Needham D. Development of a mobility scale for use in a multicentre Australian and New Zealand trial of early activity and mobilisation in ICU. American Thoracic Society International Conference Abstracts B56. Neurocognitive and Neuromuscular Issues in the ICU, 2013, pp.A3123
  • Pedersen A, Psirides A, Coombs M. Models & activities of Critical Care Outreach in New Zealand hospitals: results of a national census. Nursing in Critical Care. 2014 Feb.
  • Young P, Saxena M. Fever management in intensive care patients with infections. Critical Care 2014, 18
  • Young P, Bellomo R. Fever in sepsis: is it cool to be hot? Critical Care. 2014 Feb; 18:109
2013 (12)
  • Young P, Ganter D, Nickson C. Can Social Media bridge the gap between research & practice? Crit Care Resus. 2013 Dec; 15(4):257-258
  • Young P, Weatherall M, Saxena M, Bellomo R, Freebainr R, Hammond N, van Haren F, Henderson S, McARthur C, McGuiness S, Mackle D, Myburgh J, Webb S, Beasley R and the ANZICS Clinical Trials Group. The statistical analysis plan for the HEAT trial: a multi-centre randomised placebo controlled trial of IV paracetamol in ICU patients with fever and infection. Crit Care Resus. 2013 Dec; 15(4):279-286
  • Hodgson C, Needham D, Haines K, Bailey M, Ward A, Harrold M, Young P, Zanni J, Buhr H, Higgins A, Presneill J, Berney S. Feasability and inter-rater reliability of the ICU Mobility Scale. Heart & Lung: The Journal of Acute and Critical Care. 2013 Nov
  • James S, Quirke S, McBride-Henry K. Staff perception of patient discharge from ICU to ward-based care. Nurs Crit Care. 2013 Nov;18(6):297-306
  • Buchanan S, Rosemergy I, Healy P. Drug-induced subacute cutaneous lupus erythematosus due to treatment with interferon beta-1a. N Z Med J. 2013 Aug 2;126(1379):98-101
  • Hammond NE, Saxena MK, Taylor C, Young P, Seppelt I, Glass P, Myburgh J. Temperature management of non-elective intensive care patients without neurological abnormalityes: a point prevalence study of practice in Australia and New Zealand. Crit Care & Resuscitation. 2013 Sep;15(3):228-33
  • Wirawan IM, Aldington S, Griffiths RF, Ellis CJ, Larsen PD. Cardiovascular investigations of airline pilots with excessive cardiovascular risk. Aviat Space Environ Med. 2013 Jun;84 (6): 608-12
  • Saxena M, Taylor C, Hammond N, Young P, Seppelt I, Glass P, Myburgh J. Temperature management in patients with acute neurological lesions: an Australian and New Zealand point prevalence study. Crit Care & Resuscitation. 2013 June;15(2):110-118
  • Fernando J, Ikeda T, Psirides A, Young P. Admission source predicts delay to antimicrobial therapy in septic shock - a retrospective cohort study. Crit Care & Shock (2013) 16:37-44
  • Schneider A, Eastwood G, Bellomo R, Bailey M, Lipcsey M, Pilcher D, Young P, Stow P, Santamaria J, Stachowski E, Suzuki S, Cz N, Pilcher J. Arterial carbon dioxide tension and outcome in patients admitted to the intensive care unit after cardiac arrest. Resuscitation. 2013 Mar; doi:10.1016/j.resuscitation.2013.02.014
  • Young PJ, Baker S, Cavazzoni E, Erickson SJ, Krishnan A, Kruger PS, Rashid AH, Wibrow BA. A case series of critically ill patients with anti-N-methyl-D-aspartate receptor encephalitis. Crit Care & Resuscitation. 2013 Mar;15(1):8-14
  • Psirides A, Hill J, Hurford S. A review of rapid response team activation parameters in New Zealand hospitals. Resuscitation 84 (2013) 1040-1044
2012 (22)
  • Young P, Saxena M, Bellomo R, Freebairn R, Hammond N, Haren F, Henderson S, McArthur C, McGuinness S, Mackle D, Myburgh J, Weatherall M, Webb S, Beasley R, and the ANZICS CTG. The HEAT trial: a protocol for a multicentre randomised placebo-controlled trial of IV paracetamol in ICU patients with fever and infection. Crit Care & Resuscitation. 2012 Dec; 14(4):290-296
  • Webb SA, Young P, Bellomo R. The "sweet spot" for physiological targets in critically ill patients. Crit Care & Resuscitation. 2012 Dec; 14(4):253-5
  • Tipping CJ, Young P, Romero L, Saxena M, Dulhunty J, Hodgson C. A systematic review of measurements of physical function in critically ill adults. Crit Care & Resuscitation. 2012 Dec; 14(4):302-11
  • Young P, Beasley R. The association between SpO2 values and mortality - interpret with caution. Resuscitation. 2012.09.40
  • Pilcher M, Young P, Weatherall M, Rahman I, Bonser R, Beasley R. A systematic review and meta-analysis of the cardioprotective effects of remote ischaemic preconditioning in open cardiac surgery. J R Soc Med. 2012 October; 105(10): 436-445
  • Young P, Hodgson C, Dulhunty J, Saxena M, Bailey M, Bellomo R, Davies A, Finfer S, Kruger P, Lipman J, Myburgh J, Peake S, Seppelt I, Streat S, Tate R, Webb S, and the ANZICS CTG. End points for Phase II trials in Intensive Care: Recommendations from the Australian and New Zealand Clinical Trials Group consensus panel meeting. Crit Care & Resuscitation 2012; 14; 211-215
  • Mackle D. Making ICU Research Happen: a Qualitative Descriptive Study About the Role of the Research Nurse in New Zealand Level III Intensive Care Units. Master's of Nursing, Victoria University 2012. http://hdl.handle.net/10063/2545
  • Young P, Pilcher J, Patel M, Cameron L, Braithwaite I, Weatherall M, Beasley R. Delivery of titrated oxygen via a self-inflating resuscitation bag. Resuscitation. 2010.08.330
  • Williams J, Young P, Pilcher J, Weatherall M, Miller J, Beasley R, La Flamme A. Remote ischaemic preconditioning does not alter perioperative cytokine production in high-risk cardiac surgery. Heart Asia. 2012;4:1 97-101
  • Shah N, Michel J, Ashton G, Psirides A, Mahon B, Larsen P, Sasse. Do cardiovascular risk factors predict complications in patients awaiting coronary artery bypass grafting? Heart, Lung & Circulation. August 2012; 21(8):513-514
  • Michel J, Shah N, Ashton G, Psirides A, Mahon B, Larsen P, Sasse. New Zealand cardiac clinical prioritisation system: left ventricular impairment predicts ICU length of stay after coronary artery bypass graft surgery. Heart, Lung & Circulation. August 2012; 21(8):503
  • Michel J, Shah N, Ashton G, Psirides A, Mahon B, Larsen P, Sasse. Does EuroSCORE predict preoperative complications in patients awaiting coronary artery bypass surgery: lessons from the clinical cardiac prioritisation system database. Heart, Lung & Circulation. August 2012; 21(8):503-504
  • Tripp D. Did an acute medical assessment unit improve the initial assessment and treatment of community acquired pneumonia: a retrospective audit. New Zealand Medical Journal 2012; 125 (1343) 60-67
  • Tripp D. Old Man's Friend? Resuscitation decisions in patients hospitalised with pneumonia. New Zealand Medical Journal 2012; 125 (1343) 68-74
  • Jefferies S, Saxena M, Young P. Paracetamol in critical illness: a review. Critical Care & Resuscitation 2012; 14; 74-80
  • Miles L, Bailey M, Young P, Pilcher D. Differences in mortality based on worsening ratio of partial pressure of oxygen to fraction to inspired oxygen corrected for immune system status an respiratory support. Critical Care & Resuscitation 2012; 14; 25-32
  • Poynter C, Garden A, Young PJ. Registrar sleep patterns and supervision during two different rosters in a tertiary Australasian intensive care unit. Critical Care & Resuscitation 2012; 14; 5-9
  • Young PJ, Dalley P, Garden A, Horrocks C, Mahon B, Miller J, Pilcher J, Weatherall M, WIlliams J, Young W, Beasley R. A pilot study investigating the effects of remote ischaemic preconditioning in high-risk cardiac surgery using a randomized controlled double-blind protocol. Basic Research in Cardiology 2012; 107(3):1-10
  • Young P, Beasley R, Bailey M, Bellomo R, Eastwood G, Nichol A, Pilcher D, Yunos N, Egi M, Hart G, Reade M, Cooper DJ. The association between early arterial oxygenation and mortality in ventilated patients with acute ischaemic stroke. Critical Care & Resuscitation 2012; 14; 14-19
  • Myers J, Psirides A, Hathaway K, Larsen P. Air Transport by the Wellington Flight Service: a descriptive analysis of inter-hospital transfers over a five year period in the Wellington region. New Zealand Medical Journal 2012 Mar; 125(1351)
  • Young PJ, Saxena M, Beasley R, Bellomo R, Bailey M, Pilcher D, Finfer S, Harrison D, Myburgh J, Rowan K. Early peak temperature and mortality in critically ill patients with or without infection. Intensive Care Medicine 2012 Jan 31
  • Pilcher J, Weatherall M, Shirtcliffe P, Bellomo R, Young P, Beasley R. The effect of hyperoxia following cardiac arrest - a systematic review and meta-analysis of animal trials. Resuscitation 2012 Jan 5
2011 (13)
  • Saxena MK, Hammond NE, Taylor C, Young P, Reade MC, Bellomo R, Myburgh J. A survey of fever management for febrile intensive care patients without neurological injury. Critical Care & Resuscitation 2011 Dec;13(4):238-43
  • Eastwood G, Bellomo R, Bailey M, Taori G, Pilcher D, Young P, Beasley R. Arterial oxygen tension and mortality in mechanically ventilated patients. Intensive Care Medicine 2011, online first 30/11/11. doi:10.1007/s00134-011-2419-6
  • Harper E. The development of intensive care nursing as a specialty at Wellington Hospital intensive care unit, Wellington, New Zealand, 1964-1989. Master's of Nursing thesis, Victoria University; 25-11-2011: http://hdl.handle.net/10063/1948
  • Jefferies S, Weatherall M, Young P, Eyers S, Beasley R. Systematic review and meta-analysis of the effects of antipyretic medications on mortality in Streptococcus pneumoniae infections. Postgrad Med J. doi:10.1136/postgradmedj-2011-130217
  • Saxena MK, Hammond NE, Taylor C, Young P, Reade MC, Bellomo R, Myburgh J. A survey of fever management in febrile intensive care patients without neurological injury. Critical Care 2011, 15 (Suppl 3): p18
  • Saxena M, Young P, Beasley R, Bailey M, Bellomo R, Pilcher D, Finfer S, Harrison D, Myburgh J, Rowan K. Early peak temperature and mortality in critically ill patients with and without infection. Critical Care 2011, 15 (Suppl 3): p24
  • Young P, Saxena M, Beasley R. Fever and antipyresis in infection. Medical Journal of Australia 2011; 195(8): 458-459
  • Knott C, Psirides A, Young P, Sim D. A retrospective cohort study of the effect of medical emergency teams on documentation of advance care directives. Critical Care & Resuscitation 2011;13:167-174
  • Maher L, Young P. Cardiac arrest complicating neostigmine use for bowel opening in a critically ill patient. Critical Care & Resuscitation 2011;13:192-193
  • Jefferies S, Weatherall M, Young P, Beasley R. A systematic review of the accuracy of peripheral thermometry in estimating core temperatures among febrile critically ill patients. Critical Care & Resuscitation 2011;13:194-199
  • Hicks P, Mackle D. Cause of deaths in intensive care patients within 2 years of discharge from hospital. Critical Care & Resuscitation 2010;12(2):78-82
  • Young P, Saxena M, Eastwood GM, Bellomo R, Beasley R. Fever and fever management among intensive care patients with known or suspected infection: a multicentre prospective cohort study. Critical Care & Resuscitation 2011;13(2):97-102
  • Jefferies S, Weatherall M, Young P, Eyers S, Perrin K, Beasley R. The effect of antipyretic medications on mortality in critically ill patients with infection: a systematic review & meta-analysis. Critical Care & Resuscitation 2011;13(2):125-131
2010 (4)
  • Young P, Arnold R. Intensive care triage in Australia & New Zealand. New Zealand Medical Journal 2010;123(1316):4153
  • Butt A. Nursing Care of the Chronically Critically Ill: an Exploratory Descriptive Study. Master's of Nursing Thesis, Victoria University; 2010. http://hdl.handle.net/10063/1256
  • Lawton B, Wilson L, Dinsdale R, Rose S, Brown S, Tait J, Coles C, McCaw A. Audit of severe acute maternal morbidity describing reasons for transfer and potential preventability of admissions to ICU. Australian & New Zealand Journal of Obstetrics & Gynaecology 2010;50(4):346-351
  • Jarden R, Quirke S. Improving safety & documentation in intrahospital transport - development of an intrahospital transport tool for critically ill patients. Intensive & Critical Care Nursing 2010;26(2):101-7
2009 (4)
  • Jaconelli T, Psirides A. A fulminant rash: purpura fulminans. New Zealand Medical Journal 2009;122(1293):3558
  • Psirides A, Sturland S. Withdrawal of active treatment in intensive care - what is stopped - comparison between belief & practice. Critical Care & Resuscitation 2009; 11(3):210-214
  • Jarden R. Gastric Residual Volumes in the Adult Intensive Care Patient: a Systematic Review. Master's of Nursing, Victoria University 2009. http://hdl.handle.net/10063/1188
  • Martin J, Hicks P, Norrish C, Chavan S, George C, Stow P, Hart G. Designing & implementing an Australian & New Zealand intensive care data audit study. International Journal of Health Care & Quality Assurance 2009;22(6):572-81
2008 (2)
  • Psirides A, Hicks P. Intensive Care in an unusual setting - management of pneumonia in a chimpanzee. Critical Care & Resuscitation 2008;10(1):58
  • Hicks P, Cooper DJ. The Surviving Sepsis Campaign - International guidelines for the management of severe sepsis and septic shock: 2008. An assessment by the Australian & New Zealand Intensive Care Society. Anaesthesia & Intensive Care 2008;36(2):149-151
Older (4)
  • Walker HC, Dinsdale D, Abernethy DA. Motor neuron disease presenting as postoperative respiratory failure. Anaesthesia & Intensive Care 2006 Feb;34(1):93-6
  • Ryder-Lewis M. Going home from ICU to die - a celebration of life. Nursing in Critical Care 2005;10(3):116-121
  • Ryder-Lewis M. Reliability Study of the Sedation-Agitation Scale in an Intensive Care Unit. Master's of Nursing thesis, Victoria University; 2004: http://hdl.handle.net/10063/59
  • Flabouris A. Patient referral and transportation to a regional tertiary ICU: patient demographics, severity of illness and outcome comparison with non-transported patients. Anaesthesia & Intensive Care 1999;27:385-390
ANZICS CTG Trials

Publications From The ANZICS Clinical Trials Group

ANZICS Clinical Trials Group

Wellington ICU participates in many ANZICS CTG studies. These are listed below.

  • Erythropoietin in traumatic brain injury (EPO-TBI) - a double-blind randomised controlled trial. The EPO-TBI investigators & the ANZICS Clinical Trials Group. Lancet 2015.
  • Early Parenteral Nutrition in Critically Ill Patient With Short-term Relative Contraindications to Early Enteral Nutrition - A Randomized Controlled Trial. The Early PN Investigators of the ANZICS Clinical Trials Group. JAMA 2013; 309 (20)
  • Early Intensive Care Sedation Predicts Long-term Mortality in Ventilated Critically Ill Patients - the SPICE Study Investigators & the Australian and New Zealand Intensive Care Society Clinical Trials Group. Am J Respir Crit Care Med 2012; 186(8):724-31, October 15 2012
  • Hydroxyethyl Starch or Saline for Fluid Resuscitation in Intensive Care - the CHEST Investigators & the Australian and New Zealand Intensive Care Society Clinical Trials Group. N Engl J Med 2012; 367:1901-1911, November 15 2012
  • Decompressive Craniectomy in Diffuse Traumatic Brain Injury - the DECRA Trial Investigators & the Australian and New Zealand Intensive Care Society Clinical Trials Group. N Engl J Med 2011; 364: 1493-1502, April 27 2011
  • Critical Care Services and 2009 H1N1 Influenza in Australia and New Zealand - the ANZIC Influenza Investigators. N Engl J Med 2009; 361: 1925-1934, November 12 2009
  • Hypoglycaemia and Risk of Death in Critically Ill Patients - the NICE-SUGAR Study Investigators. N Engl J Med 2012; 367: 1008-1118, September 20, 2012
  • Intensive versus Conventional Glucose Control in Critically Ill Patients - the NICE-SUGAR Study Investigators. N Engl J Med 2009; 360: 1283-1297, March 26 2009

Click on the blue & white 'Read' button to link to the article abstract in PubMed or the original journal where available online.

This page was last updated on Monday, 24 July 2017 23:32:22